Capricious restrictions designed to deny 21+ adult vapor consumers access to the flavors and products they prefer have proven effective in many states. Flavor bans have increased cigarette sales in these areas and reduced consumer choice. Adult consumers who are not interested in Big Tobacco’s products or total abstinence have few nicotine alternatives to choose from.
But this is gradually changing. From the polarizing Spree Bar to patented Nixodine-S, the market landscape has changed tremendously in 2025. Here is our guide to the alternative, active ingredient vaping alternatives available on the market today.
All products listed below intended for adults (21+) and may be habit forming. Refer to each manufacturer’s warnings. Local regulations are subject to change.
Bonguard Naturals: Nixodine
Bonguard Naturals Nixodine™ is a patented formula and has undergone significant testing. Transparency is a core value, with purity testing and toxicity research available. Nixodine has been developed as a flexible product, available in forms other than the Nixodine-S found in vaping products.
As a new product, Nixodine continues to be extensively tested for toxicity and long-term impact. According to Bongard Naturals, on the basis of this testing: “There is evidence to suggest it (Nixodine) contains less hazardous chemicals than traditional nicotine vaping or combustible cigarettes.”
Additional questions and inquiries on testing results can be directed to Bonguard Natural.
Disposable Vapes with Nixodine-S
Nixodine-S is a patented product designed for adult smokers and nicotine vapers above the age of 21. Nixodine is formulated to provide satisfaction like traditional nicotine vapes for adult users. It is also compatible with existing electronic vaping devices that use traditional VG/PG e-liquid formulations and flavors. In fact, Nixodine-S is sold in either a VG or PG base so it can be used in traditional e-liquids with next to no modification.

